Description

Benzonitrile, 5-Bromo-2,3,4-Trifluoro- is a high-value, multi-halogenated aromatic nitrile building block essential for advanced organic synthesis. Its unique structure, featuring bromine and fluorine substituents on the benzonitrile core, makes it a critical intermediate for creating complex molecules with tailored electronic and steric properties. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing active ingredients and novel materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in fluorinated drug candidates targeting CNS disorders, oncology, and anti-infectives.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine and bromine atoms enhance biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for electron-deficient aromatic units in the synthesis of organic semiconductors, liquid crystal displays (LCDs), and organic light-emitting diodes (OLEDs).
• Cross-Coupling Reactions: The bromine atom is an excellent handle for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck, Sonogashira), enabling rapid diversification of the molecular scaffold.
• Fluorine Chemistry Research: An important substrate for studying nucleophilic aromatic substitution (SNAr) and other reactions involving polyfluorinated arenes in academic and industrial R&D settings.
• Polymer & Material Science: Can be incorporated as a monomer or modifier to create specialty polymers with specific thermal, optical, or chemical resistance properties.

Basic Information

Product Name	Benzonitrile, 5-Bromo-2,3,4-Trifluoro-
CAS No.	1503508-74-4
Molecular Formula	C7HBrF3N
Molecular Weight	230.99 g/mol
Synonyms	5-Bromo-2,3,4-trifluorobenzonitrile; 2,3,4-Trifluoro-5-bromobenzonitrile; 5-Bromo-2,3,4-trifluorobenzene carbonitrile; 5-Bromo-2,3,4-trifluorophenyl cyanide; Benzonitrile, 5-bromo-2,3,4-trifluoro-; (5-Bromo-2,3,4-trifluorophenyl)carbonitrile
EINECS	Contact for details

Quality Control

Every batch of 5-Bromo-2,3,4-trifluorobenzonitrile is manufactured and analyzed under strict quality management protocols. We ensure high purity and batch-to-batch consistency through advanced analytical techniques including HPLC, GC-MS, and NMR. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.