Description

4-Amino-2-Fluoro-5-Methoxybenzonitrile is a high-purity, multi-functional aromatic nitrile building block. This compound matters for its role as a critical intermediate in the synthesis of complex, biologically active molecules, offering a unique combination of amino, fluoro, and methoxy substituents for fine-tuning chemical properties. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and anticancer drug research.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides, where the fluorine atom enhances biological activity and metabolic stability.
• Liquid Crystal & OLED Material Precursor: Serves as a building block for creating specialized dyes and electronic materials for display technologies.
• Organic Synthesis Building Block: Utilized in cross-coupling reactions (e.g., Buchwald-Hartwig amination) and cyano-group transformations to construct complex heterocycles.
• Chemical Research & Development: Employed in academic and industrial R&D for exploring new synthetic pathways and creating compound libraries for screening.

Basic Information

Product Name	4-Amino-2-Fluoro-5-Methoxybenzonitrile
CAS No.	1441723-24-5
Molecular Formula	C8H7FN2O
Molecular Weight	166.15 g/mol
Synonyms	2-Fluoro-5-methoxy-4-aminobenzonitrile; 5-Methoxy-2-fluoro-4-aminobenzonitrile; 4-Amino-2-fluoro-5-methoxybenzonitrile; Benzonitrile, 4-amino-2-fluoro-5-methoxy-; 1441723-24-5; 4-Amino-2-fluoro-5-methoxy-benzonitrile
EINECS	Contact for details

Quality Control

Our 4-Amino-2-Fluoro-5-Methoxybenzonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.