Description

3-Cyano-2,6-Difluorobenzotrifluoride, Alpha,Alpha,Alpha,2,4-Pentafluoro-m-Tolunitrile is a high-value, multi-fluorinated aromatic nitrile building block essential for advanced chemical synthesis. Its unique structure, featuring both a cyano group and multiple fluorine substituents, makes it a critical intermediate for introducing specific steric and electronic properties into target molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for creating novel active ingredients with enhanced potency and metabolic stability.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of fluorinated active pharmaceutical ingredients (APIs), particularly in oncology and central nervous system (CNS) drug discovery.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides where fluorine atoms improve bioavailability and environmental persistence.
• Liquid Crystal Materials: Serves as a precursor for fluorinated liquid crystal compounds used in high-performance displays.
• Polymer Modification: Incorporated as a monomer or cross-linking agent to create specialty polymers with enhanced chemical resistance, thermal stability, and low surface energy.
• Organic Electronics: Acts as an electron-deficient unit in the synthesis of materials for organic light-emitting diodes (OLEDs) and organic photovoltaics (OPVs).
• Fluorinated Dye & Pigment Intermediate: Used to synthesize advanced colorants with superior lightfastness and chemical stability.

Basic Information

Product Name	3-Cyano-2,6-Difluorobenzotrifluoride, Alpha,Alpha,Alpha,2,4-Pentafluoro-m-Tolunitrile
CAS No.	1440535-21-6
Molecular Formula	C9H2F5N
Molecular Weight	219.11 g/mol
Synonyms	2,6-Difluoro-3-(trifluoromethyl)benzonitrile; 3-Cyano-2,6-difluorobenzotrifluoride; 2,6-Difluoro-α,α,α-trifluoro-m-tolunitrile; 2,6-Difluoro-α,α,α-trifluoro-3-methylbenzonitrile; 3-(Trifluoromethyl)-2,6-difluorobenzonitrile; Pentafluoro-m-tolunitrile; 2,4,α,α,α-Pentafluoro-3-methylbenzonitrile; m-Tolunitrile, α,α,α,2,4-pentafluoro-
EINECS	Contact for details

Quality Control

Every batch of 3-Cyano-2,6-Difluorobenzotrifluoride is manufactured under strict quality management protocols. Our products undergo rigorous analytical testing, including GC, HPLC, NMR, and MS, to ensure identity, purity, and consistency meet the exacting standards required for research and commercial synthesis. Certificates of Analysis (COA) detailing all specifications are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (GC/HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.