Description

1-Bromo-3-Fluoro-4-Nitro-2-(Trifluoromethyl)Benzene, 6-Bromo-3-Nitro-Alpha,Alpha,Alpha,2-Tetrafluorotoluene is a high-purity, multi-functional halogenated aromatic building block of significant commercial interest. Its unique structure, featuring bromo, fluoro, nitro, and trifluoromethyl substituents, makes it a versatile and valuable intermediate for advanced synthesis. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries seeking to develop novel active ingredients with enhanced properties.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the fluorine and trifluoromethyl groups improve biological activity and environmental stability.
• Material Science Research: Serves as a monomer or functionalization agent for creating specialty polymers, liquid crystals, and organic electronic materials with specific optical or electronic properties.
• Dye and Pigment Manufacturing: Acts as an intermediate for synthesizing complex, high-performance dyes and pigments, contributing to color fastness and thermal stability.
• Cross-Coupling Reactions: The bromo substituent makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck, Stille) to construct complex biaryl systems.
• Fluorine Chemistry Library Building: A critical component for constructing diverse compound libraries in medicinal chemistry for structure-activity relationship (SAR) studies.

Basic Information

Item	Details
Product Name	1-Bromo-3-Fluoro-4-Nitro-2-(Trifluoromethyl)Benzene, 6-Bromo-3-Nitro-Alpha,Alpha,Alpha,2-Tetrafluorotoluene
CAS No.	1440535-12-5
Molecular Formula	C7H2BrF4NO2
Molecular Weight	287.99 g/mol
Synonyms	2-Bromo-6-Fluoro-3-Nitrobenzotrifluoride; 6-Bromo-3-Nitro-α,α,α,2-tetrafluorotoluene; 1-Bromo-3-fluoro-4-nitro-2-(trifluoromethyl)benzene; 2-Bromo-6-fluoro-3-nitro-α,α,α-trifluorotoluene; Benzene, 1-bromo-3-fluoro-4-nitro-2-(trifluoromethyl)-; Toluene, 6-bromo-3-nitro-α,α,α,2-tetrafluoro-; BFNBTF
EINECS	Contact for details

Quality Control

Our 1-Bromo-3-Fluoro-4-Nitro-2-(Trifluoromethyl)Benzene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and elemental analysis, to ensure high purity and batch-to-batch consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage and handling.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.