Description

Cyclopropanamine, 2-(2,3-Difluorophenyl)-, (1R,2S)- is a high-purity, stereochemically defined chiral amine building block of significant interest in advanced pharmaceutical synthesis. Its unique cyclopropane ring fused with a difluorinated aromatic system and a specific (1R,2S) configuration makes it a valuable intermediate for creating novel, potent, and selective active pharmaceutical ingredients (APIs). This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, particularly in areas requiring complex molecular architectures.

Application

• Pharmaceutical Intermediate: A critical chiral synthon in the research and development of new drug candidates, especially for central nervous system (CNS) and anti-infective therapies.
• Agrochemical Synthesis: Used in the creation of advanced, high-performance pesticides and herbicides where the difluorophenyl and cyclopropane motifs contribute to biological activity.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis to produce enantiomerically pure compounds.
• Material Science Research: Investigated as a monomer or functional additive for specialty polymers with unique optical or electronic properties.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme mechanisms and biological pathways.

Basic Information

Product Name	Cyclopropanamine, 2-(2,3-Difluorophenyl)-, (1R,2S)-
CAS No.	1427524-53-5
Molecular Formula	C9H9F2N
Molecular Weight	169.17 g/mol
Synonyms	(1R,2S)-2-(2,3-Difluorophenyl)cyclopropanamine; (1R,2S)-2-(2,3-Difluorophenyl)cyclopropylamine; (1R,2S)-rel-2-(2,3-Difluorophenyl)cyclopropanamine; 2-(2,3-Difluorophenyl)cyclopropanamine (1R,2S)-isomer; (1R,2S)-2-(2,3-Difluorophenyl)-1-cyclopropanamine; UNII-Contact for details; Chiral difluorophenyl cyclopropane amine
EINECS	Contact for details

Quality Control

Our Cyclopropanamine, 2-(2,3-Difluorophenyl)-, (1R,2S)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with exacting research and development standards. Certificates of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.