Description

(Des-Gly10,D-Tyr5,D-Ser(Tbu)6,Pro-Nhet9)-Lhrh is a synthetic peptide analog of Gonadotropin-Releasing Hormone (GnRH), specifically engineered for enhanced stability and targeted biological activity. This high-purity compound is critical for advanced research and development in endocrinology and reproductive medicine. It serves as a key intermediate and reference standard for pharmaceutical companies, academic research institutions, and CROs developing novel therapeutic agents and diagnostic tools.

Application

• Pharmaceutical R&D: Serves as a crucial intermediate in the synthesis of novel GnRH agonist or antagonist drug candidates for treating hormone-dependent conditions.
• Biochemical Research: Used as a high-purity reference standard in receptor binding assays, signal transduction studies, and structure-activity relationship (SAR) analysis.
• Veterinary Medicine Development: Applied in research for developing fertility control and reproductive management solutions in animals.
• Diagnostic Kit Manufacturing: Utilized in the production of calibration standards and controls for immunoassays measuring hormonal levels.
• Peptide Library Synthesis: Acts as a specialized building block for constructing focused peptide libraries for high-throughput screening.
• Academic & Clinical Studies: Supports fundamental research into the GnRH receptor mechanism and its role in various physiological and pathological processes.

Basic Information

Item	Details
Product Name	(Des-Gly10,D-Tyr5,D-Ser(Tbu)6,Pro-Nhet9)-Lhrh
CAS No.	1426174-33-5
Molecular Formula	C58H81N15O13
Molecular Weight	1180.4 g/mol
Synonyms	GnRH Analog (modified); LHRH Derivative; (Des-Gly10,D-Tyr5,D-Ser(tBu)6,Pro-NHEt9)-LHRH; Gonadorelin Analog; pGlu-His-Trp-Ser-Tyr-D-Tyr-D-Ser(tBu)-Leu-Arg-Pro-NHEt; Modified Luteinizing Hormone-Releasing Hormone; D-Ser(tBu)6, Pro-NHEt9-LHRH; D-Tyr5, D-Ser(tBu)6, Des-Gly10, Pro-NHEt9-GnRH
EINECS	Contact for details

Quality Control

Every batch of our (Des-Gly10,D-Tyr5,D-Ser(Tbu)6,Pro-Nhet9)-Lhrh is manufactured under strict quality management systems and undergoes comprehensive analytical testing. We ensure compliance with stringent purity standards suitable for research and development applications. A detailed Certificate of Analysis (COA), providing results from HPLC, MS, and amino acid analysis, is provided with each shipment to guarantee traceability, identity, and purity.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (MS)	Consistent with theoretical molecular weight
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 2.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%
Solubility	Soluble in DMSO, Acetic Acid; Slightly soluble in Water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.