Description

5-(Difluoromethyl)-1-Methyl-1H-1,2,3-Triazole-4-Carboxylic Acid is a high-value, functionalized triazole derivative serving as a critical building block in advanced organic synthesis. Its unique structure, featuring a difluoromethyl group and a carboxylic acid moiety, makes it an essential precursor for developing novel active pharmaceutical ingredients (APIs) and agrochemicals. This compound is primarily targeted at research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries seeking to incorporate fluorinated heterocycles into their molecular designs.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of fluorinated drug candidates, particularly in antiviral, anticancer, and anti-inflammatory research.
• Agrochemical Active Ingredient Development: Used in creating novel herbicides, fungicides, and insecticides where the difluoromethyl-triazole scaffold can enhance biological activity and metabolic stability.
• Ligand and Catalyst Synthesis: Serves as a precursor for constructing complex ligands used in catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Incorporated into polymers and advanced materials to modify physical properties like solubility and thermal stability.
• Chemical Biology Probes: Utilized in the design of molecular probes and tags for studying biological processes due to its fluorinated label potential.
• Custom Synthesis and Contract Manufacturing: Supplied for bespoke organic synthesis projects requiring high-purity, specialized fluorinated intermediates.

Basic Information

Product Name	5-(Difluoromethyl)-1-Methyl-1H-1,2,3-Triazole-4-Carboxylic Acid
CAS No.	1423028-04-9
Molecular Formula	C5H5F2N3O2
Molecular Weight	177.11 g/mol
Synonyms	1-Methyl-5-(difluoromethyl)-1H-1,2,3-triazole-4-carboxylic acid; 5-(Difluoromethyl)-1-methyl-1,2,3-triazole-4-carboxylic acid; 1-Methyl-5-(difluoromethyl)-1H-1,2,3-triazole-4-carboxylic acid; 4-Carboxy-1-methyl-5-(difluoromethyl)-1,2,3-triazole; DFMT-CA; CAS 1423028-04-9
EINECS	Contact for details

Quality Control

Our production of 5-(Difluoromethyl)-1-Methyl-1H-1,2,3-Triazole-4-Carboxylic Acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including HPLC, NMR, and MS to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We operate under a cGMP-compliant quality system suitable for pharmaceutical intermediate applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.