Description

cis-3-Fluorooxan-4-Ol is a fluorinated oxane derivative, a high-purity chiral building block of significant interest in advanced organic synthesis. Its unique structure, featuring a fluorine atom and a hydroxyl group on a saturated oxane ring, makes it a valuable synthon for introducing stereochemical complexity and modulating physicochemical properties in target molecules. This compound is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and anti-infective therapeutics.
• Agrochemical Research: Used in the development of advanced pesticides and herbicides, where the fluorine atom can enhance biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a scaffold for creating chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science: A potential monomer or modifier for synthesizing specialty polymers with specific optical or surface properties.
• Chemical Biology Probes: Utilized in the design of molecular probes to study enzyme mechanisms and biological pathways.

Basic Information

Product Name	cis-3-Fluorooxan-4-Ol
CAS No.	1422188-18-8
Molecular Formula	C5H9FO2
Molecular Weight	120.12 g/mol
Synonyms	cis-3-Fluorooxane-4-ol; 3-Fluorooxan-4-ol (cis-); 4-Oxanyl-3-ol, 3-fluoro-, (3R,4S)-rel-; (3R,4S)-3-Fluorotetrahydro-2H-pyran-4-ol; rel-(3R,4S)-3-Fluorooxan-4-ol; 3-Fluoro-4-hydroxyoxane; Fluorinated oxane alcohol; THP-fluoro alcohol derivative
EINECS	Contact for details

Quality Control

Our cis-3-Fluorooxan-4-Ol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for research and process development. A detailed Certificate of Analysis (COA) providing specifications for identity, purity (assay), enantiomeric excess, and impurities is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.