Description

Benzene, 2-Bromo-1-Fluoro-4-Nitro-3-(Trifluoromethyl)- is a highly functionalized aromatic building block designed for advanced synthetic chemistry. This compound is critical for introducing multiple halogen and nitro substituents in a single, controlled step, enabling the rapid construction of complex molecular architectures. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring halogenated aromatic cores for bioactivity or further functionalization.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides where the trifluoromethyl and nitro groups confer specific biological properties and stability.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers, liquid crystals, and organic electronic materials.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic aromatic substitution due to its reactive bromo and fluoro substituents.
• Dye and Pigment Intermediate: Facilitates the production of complex, high-performance colorants for industrial applications.

Basic Information

Product Name	Benzene, 2-Bromo-1-Fluoro-4-Nitro-3-(Trifluoromethyl)-
CAS No.	1421599-49-6
Molecular Formula	C7H2BrF4NO2
Molecular Weight	287.99 g/mol
Synonyms	2-Bromo-1-fluoro-4-nitro-3-(trifluoromethyl)benzene; 1-Bromo-2-fluoro-5-nitro-4-(trifluoromethyl)benzene; 3-Bromo-4-fluoro-1-nitro-2-(trifluoromethyl)benzene; 2-Bromo-1-fluoro-4-nitro-α,α,α-trifluorotoluene; Benzene, 1-bromo-2-fluoro-5-nitro-4-(trifluoromethyl)-; BRN 1421599-49-6
EINECS	Contact for details

Quality Control

Our Benzene, 2-Bromo-1-Fluoro-4-Nitro-3-(Trifluoromethyl)- is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and storage should minimize exposure to direct light.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Melting Point	Contact for details
Heavy Metals	<20 ppm
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	<0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.