Description

4-Amino-2-Ethoxy-5-Fluorobenzonitrile is a high-purity, multi-functional aromatic nitrile building block designed for advanced chemical synthesis. This compound matters for its role as a critical intermediate in the development of active pharmaceutical ingredients (APIs) and specialty agrochemicals, where its unique substitution pattern enables precise molecular construction. It is primarily needed by research and development chemists, process scale-up engineers, and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors seeking reliable, high-quality intermediates for complex synthesis.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in kinase inhibitor and other small-molecule therapeutic research.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides, leveraging the fluorine and nitrile functionalities.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for creating specialized aromatic cores used in electronic display technologies.
• Dye & Pigment Intermediate: Employed in the production of high-performance, color-fast dyes and organic pigments.
• Cross-Coupling Reactions: The amino and halogenated (fluoro) groups make it a versatile substrate for Suzuki, Buchwald-Hartwig, and other palladium-catalyzed coupling reactions.
• Chemical Research & Development: A valuable reagent for academic and industrial R&D exploring new heterocyclic compounds and functional materials.

Basic Information

Product Name	4-Amino-2-Ethoxy-5-Fluorobenzonitrile
CAS No.	1420800-17-4
Molecular Formula	C9H9FN2O
Molecular Weight	180.18 g/mol
Synonyms	5-Fluoro-2-ethoxy-4-aminobenzonitrile; 4-Amino-5-fluoro-2-ethoxybenzonitrile; 2-Ethoxy-5-fluoro-4-aminobenzonitrile; Benzonitrile, 4-amino-2-ethoxy-5-fluoro-; 1420800-17-4; 4-Cyano-3-ethoxy-6-fluoroaniline
EINECS	Contact for details

Quality Control

Our 4-Amino-2-Ethoxy-5-Fluorobenzonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical and agrochemical applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Assay	97.0% - 102.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.