Description

2-Bromo-4-Fluoro-5-Methoxybenzonitrile is a high-value, multi-functional aromatic nitrile building block. This compound is critical for the synthesis of complex molecules, particularly in advanced pharmaceutical and agrochemical research and development. It is primarily sought after by R&D chemists and process development scientists in the life sciences sector for constructing novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), especially in kinase inhibitor and CNS drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, leveraging the fluorine and bromine substituents for bioactivity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of organic semiconductors, liquid crystals, and advanced polymers due to its electron-withdrawing nitrile group and halogenated structure.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	2-Bromo-4-Fluoro-5-Methoxybenzonitrile
CAS No.	1410791-42-2
Molecular Formula	C8H5BrFNO
Molecular Weight	230.04 g/mol
Synonyms	5-Methoxy-2-bromo-4-fluorobenzonitrile; 4-Fluoro-5-methoxy-2-bromobenzonitrile; Benzonitrile, 2-bromo-4-fluoro-5-methoxy-; 2-Bromo-4-fluoro-5-methoxybenzenecarbonitrile
EINECS	Contact for details

Quality Control

Our 2-Bromo-4-Fluoro-5-Methoxybenzonitrile is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with customer specifications and internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.