Description

Benzonitrile, 5-Fluoro-4-Hydroxy-2-Methyl- is a high-purity fluorinated aromatic nitrile derivative, serving as a critical advanced pharmaceutical intermediate and versatile building block in organic synthesis. Its unique molecular structure, featuring both a nitrile group and a fluorinated hydroxy-methyl substitution pattern, makes it indispensable for constructing complex molecules with targeted biological activity. This compound is primarily required by pharmaceutical R&D and fine chemical manufacturing sectors for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key synthon in the research and production of fluorinated drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Building block for developing advanced herbicides and pesticides, where the fluorine atom enhances bioavailability and environmental stability.
• Liquid Crystal Materials: Used in the synthesis of fluorinated components for high-performance liquid crystal displays (LCDs).
• Organic Light-Emitting Diodes (OLEDs): Serves as a precursor for electron-transport materials or emissive layer dopants.
• Complex Ligand Synthesis: Intermediate for creating specialized ligands used in catalysis and metal-organic frameworks (MOFs).
• Fluorine Chemistry Research: A valuable substrate for studying fluorination reactions and structure-activity relationships (SAR) in medicinal chemistry.

Basic Information

Product Name	Benzonitrile, 5-Fluoro-4-Hydroxy-2-Methyl-
CAS No.	1394936-27-6
Molecular Formula	C8H6FNO
Molecular Weight	151.14 g/mol
Synonyms	5-Fluoro-4-hydroxy-2-methylbenzonitrile; 2-Methyl-5-fluoro-4-hydroxybenzonitrile; 4-Hydroxy-5-fluoro-2-methylbenzonitrile; 5-Fluoro-2-methyl-4-hydroxybenzonitrile; 4-Cyano-2-fluoro-5-methylphenol; 2-Fluoro-5-methyl-4-cyanophenol; AI3-71031; BRN 2992296
EINECS	Contact for details

Quality Control

Our Benzonitrile, 5-Fluoro-4-Hydroxy-2-Methyl- is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available upon request, confirming compliance with client specifications and relevant industry standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases. This material is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if specified.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Single Unknown Impurity (HPLC)	≤0.5%
Total Impurities (HPLC)	≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.