Description

2-Fluoro-4-(3-Nitrophenyl)Benzonitrile is a high-purity, multi-functional aromatic nitrile building block. This compound is valued for its unique molecular scaffold, which combines electron-withdrawing nitrile and nitro groups with a fluorine substituent, making it a versatile intermediate in advanced synthesis. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecules and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and CNS drug discovery programs.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides, leveraging its aromatic core for bioactivity.
• Liquid Crystal & OLED Materials: Serves as a precursor for advanced electronic materials, where its planar structure and substituents influence electronic properties.
• Organic Synthesis Reagent: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and as a precursor for heterocyclic compounds like benzimidazoles and quinolines.
• Chemical Biology Probe: Useful for labeling and bioconjugation studies due to the reactivity of the nitrile and nitro functional groups.

Basic Information

Product Name	2-Fluoro-4-(3-Nitrophenyl)Benzonitrile
CAS No.	1393441-74-1
Molecular Formula	C13H7FN2O2
Molecular Weight	242.21 g/mol
Synonyms	4-(3-Nitrophenyl)-2-fluorobenzonitrile; 2-Fluoro-4-(3-nitrophenyl)benzonitrile; 3-(4-Cyano-3-fluorophenyl)nitrobenzene; 2-Fluoro-4-(m-nitrophenyl)benzonitrile; [1,1'-Biphenyl]-3-carbonitrile, 2'-fluoro-3'-nitro-; 2'-Fluoro-3'-nitro[1,1'-biphenyl]-3-carbonitrile
EINECS	Contact for details

Quality Control

Our 2-Fluoro-4-(3-Nitrophenyl)Benzonitrile is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications and relevant industry standards for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids, bases, and oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.