Description

4-[2-(Trifluoromethyl)Phenyl]Oxane-4-Carbonitrile is a high-value, fluorinated organic building block characterized by its unique oxane (tetrahydropyran) ring and nitrile functionality. This compound matters as a versatile and critical intermediate in modern synthetic chemistry, enabling the construction of complex molecular architectures. It is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, particularly those requiring the trifluoromethyl group for enhanced metabolic stability and lipophilicity.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of new drug candidates, especially for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Synthesis: Used in the creation of advanced herbicides and fungicides where the trifluoromethyl group improves biological activity and environmental profile.
• Material Science Research: Acts as a precursor for specialty monomers or ligands in the development of advanced polymers and functional materials.
• Chemical Biology Probes: Employed in the synthesis of labeled compounds or molecular probes for studying biological pathways and enzyme interactions.
• Custom Synthesis & Contract Manufacturing: A crucial starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	4-[2-(Trifluoromethyl)Phenyl]Oxane-4-Carbonitrile
CAS No.	1393330-54-5
Molecular Formula	C13H12F3NO
Molecular Weight	255.24 g/mol
Synonyms	4-[2-(Trifluoromethyl)phenyl]tetrahydro-2H-pyran-4-carbonitrile; 4-(2-(Trifluoromethyl)phenyl)tetrahydro-2H-pyran-4-carbonitrile; 2H-Pyran-4-carbonitrile, 4-[2-(trifluoromethyl)phenyl]tetrahydro-; 4-(α,α,α-Trifluoro-o-tolyl)tetrahydropyran-4-carbonitrile; 4-(2-Trifluoromethylphenyl)tetrahydropyran-4-carbonitrile; 4-(2-Trifluoromethylphenyl)-4-cyanotetrahydropyran
EINECS	Contact for details

Quality Control

Our 4-[2-(Trifluoromethyl)Phenyl]Oxane-4-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to supply reliability and traceability supports your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of ignition. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.