Description

1-Fluoro-3,3-Dimethyl-1,2-Benziodoxole is a specialized hypervalent iodine(III) reagent, a key building block for the efficient and selective introduction of fluorine atoms into organic molecules. This compound matters because it serves as a powerful electrophilic fluorinating agent, enabling critical C-F bond formation in complex synthetic pathways with high precision. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for the synthesis of novel fluorinated compounds.

Application

• Electrophilic Fluorination Reagent: A key reagent for the selective fluorination of enolates, silyl enol ethers, and other carbon nucleophiles in organic synthesis.
• Pharmaceutical Intermediate Synthesis: Used in the development and production of active pharmaceutical ingredients (APIs) that contain fluorine, a common moiety in modern drugs to enhance metabolic stability and bioavailability.
• Agrochemical Research: Applied in the synthesis of novel fluorinated pesticides and herbicides, where fluorine atoms can improve activity and environmental persistence.
• Material Science Precursor: Serves as a fluorinating agent in the creation of specialty polymers and advanced materials with tailored surface properties.
• Radiochemistry & Tracer Development: Potential use as a precursor or reagent in the synthesis of compounds for Positron Emission Tomography (PET) imaging, particularly for introducing fluorine-18.
• Methodology Development in Academia: A valuable tool for academic researchers developing new fluorination methodologies and exploring reaction mechanisms.

Basic Information

Product Name	1-Fluoro-3,3-Dimethyl-1,2-Benziodoxole
CAS No.	1391728-13-4
Molecular Formula	C8H8FIO
Molecular Weight	290.06 g/mol
Synonyms	1-Fluoro-3,3-dimethyl-1λ3,2-benziodoxole; 3,3-Dimethyl-1-fluoro-1,2-benziodoxole; DFBT; 1-Fluoro-3,3-dimethylbenziodoxole; (Difluoroiodo)benzene derivative; Electrophilic fluorinating reagent; Hypervalent iodine(III) fluoride
EINECS	Contact for details

Quality Control

Our 1-Fluoro-3,3-Dimethyl-1,2-Benziodoxole is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable to support our clients in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Recommended storage temperature is 2-8°C. Due to its hygroscopic (moisture-sensitive) nature, containers should be kept sealed under an inert atmosphere (e.g., argon or nitrogen) when not in use to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.