Description

2-Amino-3-Fluoropropan-1-Ol Hydrochloride is a fluorinated amino alcohol hydrochloride salt, a valuable chiral building block in advanced organic synthesis. This compound matters for its role in introducing both fluorine and amino alcohol functionalities into target molecules, which is critical for modulating the physicochemical and biological properties of pharmaceuticals. It is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, particularly in medicinal chemistry programs targeting CNS disorders and metabolic diseases.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of fluorinated drug candidates, including protease inhibitors and kinase inhibitors.
• Agrochemical Synthesis: Used in the research and production of advanced, fluorinated pesticides and herbicides to enhance efficacy and environmental profile.
• Peptidomimetics & Bioactive Molecules: Serves as a building block for constructing fluorinated amino acid analogs and peptide mimetics in drug discovery.
• Chemical Biology Probes: Employed in the synthesis of fluorinated probes and ligands for studying enzyme mechanisms and receptor interactions.
• Material Science Research: Potential monomer or modifier in the synthesis of specialized polymers and functional materials.
• Academic & Industrial R&D: A versatile reagent for methodological development in asymmetric synthesis and fluorine chemistry.

Basic Information

Product Name	2-Amino-3-Fluoropropan-1-Ol Hydrochloride
CAS No.	1384428-30-1
Molecular Formula	C₃H₉ClFNO
Molecular Weight	141.56 g/mol
Synonyms	3-Fluoro-2-aminopropanol Hydrochloride; 2-Amino-3-fluoropropanol HCl; 1-Propanol, 2-amino-3-fluoro-, hydrochloride; (2R/S)-2-Amino-3-fluoropropan-1-ol hydrochloride; 3-Fluoroalaninol Hydrochloride; β-Fluoroalaninol Hydrochloride; FAOL-HCl; 1384428-30-1
EINECS	Contact for details

Quality Control

Our 2-Amino-3-Fluoropropan-1-Ol Hydrochloride is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral purity assessment, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation by atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee (Specific enantiomer available)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.