Description

Abiraterone Mesylate is a high-purity pharmaceutical intermediate and active pharmaceutical ingredient (API) of significant therapeutic importance. Its primary value lies in its role as a potent and selective inhibitor of CYP17, a key enzyme in androgen biosynthesis. This compound is essential for the development and production of advanced oncology treatments, particularly for hormone-refractory prostate cancer. It is a critical raw material for pharmaceutical manufacturers, research institutions, and contract development and manufacturing organizations (CDMOs) engaged in innovative cancer therapy development.

Application

• Active Pharmaceutical Ingredient (API) for the formulation of abiraterone acetate-based anti-cancer drugs.
• Pharmaceutical Intermediate in the synthesis of final drug products targeting androgen-sensitive cancers.
• Research & Development of novel therapeutic agents for prostate cancer and other hormone-dependent conditions.
• Reference Standard for analytical method development, validation, and quality control in pharmaceutical laboratories.
• Preclinical and Clinical Studies as a key material for pharmacological and toxicological evaluations.
• Process Chemistry for scale-up and optimization of manufacturing routes in a GMP environment.

Basic Information

Product Name	Abiraterone Mesylate
CAS No.	1382475-35-5
Molecular Formula	C₂₈H₃₅NO₅S
Molecular Weight	485.65 g/mol
Synonyms	Abiraterone Methanesulfonate; (3β)-17-(3-Pyridinyl)androsta-5,16-dien-3-yl acetate methanesulfonate; CB-7630 mesylate; Abiraterone mesylate salt; Zytiga intermediate; 17-(3-Pyridyl)androsta-5,16-dien-3β-yl acetate methanesulfonate
EINECS	Contact for details

Quality Control

Our Abiraterone Mesylate is manufactured under strict quality management systems to ensure it meets the rigorous standards required for pharmaceutical applications. Each batch is subjected to comprehensive analytical testing, including identity confirmation, purity assay, and impurity profiling via advanced techniques like HPLC and LC-MS. We provide full traceability and support regulatory filings. A detailed Certificate of Analysis (COA) is available for every lot, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert conditions or in a desiccator to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.5%
Related Substances (HPLC)	Total impurities ≤1.5% Any single unknown impurity ≤0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤0.5%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.