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2-Fluoro-4-(3-Methylphenyl)Benzonitrile CAS NO 1381944-81-5


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CAS No.:1381944-81-5

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

2-Fluoro-4-(3-Methylphenyl)Benzonitrile is a high-value, multi-functional aromatic nitrile building block. This compound matters for its role as a critical intermediate in the synthesis of advanced materials and active pharmaceutical ingredients (APIs), offering a unique combination of a fluorine substituent and a benzonitrile core. Pharmaceutical, agrochemical, and advanced material research and development teams need it to create novel compounds with targeted properties.

Application

  • Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in kinase inhibitor and CNS-active molecule libraries.
  • Agrochemical Synthesis: Used in the production of novel herbicides and fungicides, where the fluorine atom enhances biological activity and metabolic stability.
  • Liquid Crystal & OLED Material Precursor: Serves as a building block for advanced electronic materials used in displays and lighting.
  • Polymer & Resin Modifier: Incorporated into specialty polymers to alter thermal stability, solubility, and dielectric properties.
  • Organic Synthesis & Catalysis Research: Employed in cross-coupling reactions and as a ligand precursor in catalytic systems.
  • Fluorescent Dye & Sensor Development: Acts as a core structure for creating novel fluorophores and chemical sensing agents.

Basic Information

Product Name 2-Fluoro-4-(3-Methylphenyl)Benzonitrile
CAS No. 1381944-81-5
Molecular Formula C14H10FN
Molecular Weight 211.24 g/mol
Synonyms 2-Fluoro-4-(m-tolyl)benzonitrile; 4-(3-Methylphenyl)-2-fluorobenzonitrile; 2-Fluoro-4-(3-methylphenyl)benzonitrile; [1,1'-Biphenyl]-3-carbonitrile, 2'-fluoro-4'-methyl-; 2'-Fluoro-4'-methyl-[1,1'-biphenyl]-3-carbonitrile; 3-(2-Fluoro-4-cyanophenyl)toluene; m-Tolyl-2-fluoro-4-cyanobenzene
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Quality Control

Our 2-Fluoro-4-(3-Methylphenyl)Benzonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your R&D and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Identification (HPLC) Conforms to reference
Purity (HPLC) ≥ 97.0%
Water Content (KF) ≤ 0.5%
Residue on Ignition ≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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