Description

2-Fluoro-4-(3-Methoxyphenyl)Benzonitrile is a high-purity, specialized aromatic nitrile derivative featuring a fluorinated biphenyl-like structure. This compound serves as a critical advanced pharmaceutical intermediate and a versatile building block in modern organic synthesis. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and material science sectors for developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in kinase inhibitor and CNS-active compound libraries.
• Agrochemical Synthesis: Used as a precursor for creating novel herbicides and fungicides with enhanced activity and selectivity.
• Liquid Crystal & OLED Material Research: Serves as a core structure for developing fluorinated liquid crystal compounds and organic light-emitting diode (OLED) materials.
• Organic Synthesis Building Block: Enables Suzuki-Miyaura and other cross-coupling reactions to construct complex biaryl systems for various applications.
• Chemical Biology Probe Development: Utilized in the design of fluorescent tags and molecular probes for studying biological processes.

Basic Information

Product Name	2-Fluoro-4-(3-Methoxyphenyl)Benzonitrile
CAS No.	1381944-62-2
Molecular Formula	C14H10FNO
Molecular Weight	227.24 g/mol
Synonyms	4-(3-Methoxyphenyl)-2-fluorobenzonitrile; 2-Fluoro-4-(3-methoxyphenyl)benzonitrile; 2-Fluoro-4-(m-anisyl)benzonitrile; [1,1'-Biphenyl]-3-carbonitrile, 2'-fluoro-4'-methoxy-; 2'-Fluoro-4'-methoxy[1,1'-biphenyl]-3-carbonitrile; Benzonitrile, 2-fluoro-4-(3-methoxyphenyl)-; 1381944-62-2
EINECS	Contact for details

Quality Control

Our production of 2-Fluoro-4-(3-Methoxyphenyl)Benzonitrile adheres to stringent in-process controls and final release testing to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) detailing purity, identity, and impurity profiles, typically determined by HPLC, GC, NMR, and mass spectrometry. Our quality management system supports development under cGMP guidelines for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.