Description

4-(2-Chloro-5-Methylphenyl)-2-Fluorobenzonitrile is a high-purity fluorinated benzonitrile derivative, serving as a critical advanced intermediate in modern organic synthesis. Its value lies in its unique molecular scaffold, which is designed to introduce specific steric and electronic properties into target molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to build novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of new drug candidates targeting various disease pathways.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine and nitrile groups contribute to biological activity and metabolic stability.
• Material Science Research: Serves as a precursor for the development of specialty chemicals, liquid crystals, and functional polymers requiring specific aromatic fluorinated units.
• Organic Light-Emitting Diode (OLED) Materials: Acts as a synthetic intermediate for electron-transport or host materials in OLED devices due to its rigid, conjugated structure.
• Chemical Research & Development: Employed in academic and industrial R&D labs for method development, catalysis studies, and exploring novel chemical reactions involving fluorinated aromatics.

Basic Information

Product Name	4-(2-Chloro-5-Methylphenyl)-2-Fluorobenzonitrile
CAS No.	1381944-54-2
Molecular Formula	C14H9ClFN
Molecular Weight	245.68 g/mol
Synonyms	2-Fluoro-4-(2-chloro-5-methylphenyl)benzonitrile; 4-(2-Chloro-5-methylphenyl)-2-fluorobenzonitrile; 2-Chloro-5-methyl-4'-fluorobenzonitrile; 2-Fluoro-4'-(2-chloro-5-methylphenyl)benzonitrile; Benzonitrile, 4-(2-chloro-5-methylphenyl)-2-fluoro-; 1381944-54-2
EINECS	Contact for details

Quality Control

Our 4-(2-Chloro-5-Methylphenyl)-2-Fluorobenzonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing identity, assay, and impurity profiles to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong bases and strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.