Description

Methyl 2-Cyano-2-(4-Fluoro-2-Nitrophenyl)Acetate is a high-value, multi-functional chemical intermediate featuring a unique molecular scaffold. Its structure, containing cyano, ester, fluoro, and nitro substituents, makes it a critical building block for synthesizing complex heterocyclic compounds and active pharmaceutical ingredients (APIs). This compound is essential for research and development chemists and process engineers in the pharmaceutical and agrochemical sectors who require reliable, high-purity intermediates for advanced synthesis.

Application

This versatile intermediate is primarily used in the synthesis of complex molecules. Its applications include:

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-inflammatory agents, and kinase inhibitors.
• Agrochemical Synthesis: Used in the development of advanced herbicides and pesticides, leveraging the fluorine atom for enhanced biological activity and metabolic stability.
• Material Science Research: Serves as a monomer or building block for creating specialized polymers and organic electronic materials.
• Dye and Pigment Intermediate: Utilized in the synthesis of complex nitro- and cyano-substituted dyes and pigments.
• Academic & Contract Research: A valuable reagent for methodological development in organic synthesis and medicinal chemistry research within universities and CROs.

Basic Information

Product Name	Methyl 2-Cyano-2-(4-Fluoro-2-Nitrophenyl)Acetate
CAS No.	1381944-42-8
Molecular Formula	C10H7FN2O4
Molecular Weight	238.17 g/mol
Synonyms	Methyl (4-Fluoro-2-nitrophenyl)(cyano)acetate; 2-Cyano-2-(4-fluoro-2-nitrophenyl)acetic acid methyl ester; Methyl α-cyano-4-fluoro-2-nitrobenzeneacetate; Acetic acid, 2-cyano-2-(4-fluoro-2-nitrophenyl)-, methyl ester; (4-Fluoro-2-nitrophenyl)(cyano)acetic acid methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 2-Cyano-2-(4-Fluoro-2-Nitrophenyl)Acetate is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP guidelines where applicable, ensuring reliability for your most demanding synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber-colored or stored in light-resistant secondary packaging.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.