Description

4-Chloro-3-Fluoro-5-Nitrobenzonitrile is a high-value, multi-functional aromatic nitrile building block. This compound matters for its unique molecular architecture, which combines halogen substituents and a nitro group to enable precise synthetic modifications in advanced chemical synthesis. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting kinase inhibition or other enzyme-related pathways.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and pesticides, leveraging its halogenated nitrobenzonitrile core.
• Material Science Research: Serves as a monomer or functionalization agent in the creation of specialty polymers and advanced organic electronic materials.
• Ligand and Catalyst Development: Employed in the preparation of complex chelating ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Utilized as a scaffold for developing fluorescent tags or activity-based probes for biological target identification.
• Custom Synthesis and Contract Manufacturing: A critical building block for custom synthesis projects requiring specific halogen and nitro functional group patterns.

Basic Information

Product Name	4-Chloro-3-Fluoro-5-Nitrobenzonitrile
CAS No.	1380921-45-8
Molecular Formula	C7H2ClFN2O2
Molecular Weight	200.56 g/mol
Synonyms	5-Nitro-3-fluoro-4-chlorobenzonitrile; 3-Fluoro-4-chloro-5-nitrobenzonitrile; Benzonitrile, 4-chloro-3-fluoro-5-nitro-; 4-Chloro-3-fluoro-5-nitro-benzonitrile; 1380921-45-8; 4-Chloro-3-fluoro-5-nitrobenzenecarbonitrile
EINECS	Contact for details

Quality Control

Our 4-Chloro-3-Fluoro-5-Nitrobenzonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) documenting all critical quality attributes are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive nature and potential for oxidation, it is recommended to store the material under an inert atmosphere for long-term preservation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.