Description

2-Bromo-4-Fluoro-5-Nitrobenzonitrile is a high-purity, multi-functional aromatic nitrile building block designed for advanced chemical synthesis. This compound matters for its unique halogenated and nitrated structure, which provides multiple reactive sites for constructing complex molecular architectures. It is primarily needed by researchers and manufacturers in the pharmaceutical and agrochemical industries for developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, leveraging its halogen and nitro groups for bioactivity.
• Material Science Research: Serves as a precursor for the development of specialty polymers, liquid crystals, and organic electronic materials due to its aromatic core and functional handles.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed reactions (e.g., Suzuki, Buchwald-Hartwig) to introduce the bromo-fluoro-nitrobenzonitrile moiety into more complex systems.
• Dye and Pigment Intermediate: Utilized in the synthesis of specialized dyes and pigments where the nitro and cyano groups contribute to color and stability properties.

Basic Information

Product Name	2-Bromo-4-Fluoro-5-Nitrobenzonitrile
CAS No.	1379371-66-0
Molecular Formula	C7H2BrFN2O2
Molecular Weight	244.99 g/mol
Synonyms	2-Bromo-4-fluoro-5-nitrobenzonitrile; Benzonitrile, 2-bromo-4-fluoro-5-nitro-; 5-Nitro-2-bromo-4-fluorobenzonitrile; 4-Fluoro-5-nitro-2-bromobenzonitrile; 2-Bromo-4-fluoro-5-nitro-benzonitrile; 1379371-66-0; 2-Br-4-F-5-NO2-BzCN
EINECS	Contact for details

Quality Control

Our 2-Bromo-4-Fluoro-5-Nitrobenzonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and scale-up. Certificates of Analysis (COA) with detailed chromatograms and spectral data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.