Description

2-Amino-6-Fluoro-3-Nitro-Benzonitrile is a high-purity, multi-functional aromatic nitrile building block of significant importance in advanced organic synthesis. Its unique molecular structure, featuring amino, fluoro, and nitro substituents, makes it a versatile intermediate for constructing complex heterocyclic systems and functional materials. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of fluorinated drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine atom enhances biological activity and metabolic stability.
• Material Science Research: Serves as a building block for the development of specialty polymers, liquid crystals, and organic electronic materials due to its electron-withdrawing nitro and nitrile groups.
• Dye and Pigment Intermediate: Employed in the synthesis of complex, color-fast azo dyes and high-performance pigments.
• Chemical Research & Development: A valuable reagent for academic and industrial R&D in organic chemistry, facilitating studies in nucleophilic aromatic substitution and cyclization reactions.

Basic Information

Product Name	2-Amino-6-Fluoro-3-Nitro-Benzonitrile
CAS No.	1378862-33-9
Molecular Formula	C7H4FN3O2
Molecular Weight	181.12 g/mol
Synonyms	2-Amino-6-fluoro-3-nitrobenzonitrile; 6-Fluoro-3-nitro-2-aminobenzonitrile; 2-Cyano-3-fluoro-6-nitroaniline; Benzonitrile, 2-amino-6-fluoro-3-nitro-; 3-Nitro-2-amino-6-fluorobenzonitrile
EINECS	Contact for details

Quality Control

Every batch of 2-Amino-6-Fluoro-3-Nitro-Benzonitrile is manufactured and tested under a strict quality management system. We provide comprehensive analytical documentation, including Certificates of Analysis (COA) with data from HPLC, NMR, and MS, to ensure the identity, purity, and consistency meet the exacting standards required for pharmaceutical and agrochemical applications. Our quality commitment aligns with cGMP principles where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.