Description

2-Fluoro-5-Methoxy-3-(Trifluoromethyl)Benzonitrile, 97% is a high-purity, multi-functional aromatic nitrile building block of significant interest in advanced chemical synthesis. Its molecular structure, featuring fluorine and trifluoromethyl substituents, provides unique electronic and steric properties that are critical for modulating the activity and physicochemical profile of target molecules. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for constructing complex molecules in drug discovery and development, particularly for candidates targeting central nervous system (CNS) disorders, oncology, and inflammatory diseases.
• Agrochemical Research: Serves as a versatile precursor in the synthesis of novel herbicides, fungicides, and insecticides, where the fluorine atoms enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Used in organometallic chemistry and catalysis research to create specialized ligands that influence reaction selectivity and efficiency.
• Material Science Precursor: Employed in the research and development of advanced polymers, liquid crystals, and organic electronic materials due to its electron-withdrawing character.
• Custom Synthesis & Contract Manufacturing: An essential building block for fine chemical suppliers and CDMOs (Contract Development and Manufacturing Organizations) serving global R&D pipelines.

Basic Information

Product Name	2-Fluoro-5-Methoxy-3-(Trifluoromethyl)Benzonitrile, 97%
CAS No.	1373920-99-0
Molecular Formula	C9H5F4NO
Molecular Weight	219.14 g/mol
Synonyms	3-Cyano-2-fluoro-5-methoxybenzotrifluoride; 2-Fluoro-5-methoxy-α,α,α-trifluoromethylbenzonitrile; 2-Fluoro-α,α,α-trifluoro-5-methoxybenzonitrile; 5-Methoxy-2-fluoro-3-(trifluoromethyl)benzonitrile; 2-Fluoro-5-methoxy-3-trifluoromethylbenzonitrile; Benzeneacetonitrile, 2-fluoro-5-methoxy-α,α,α-trifluoro-
EINECS	Contact for details

Quality Control

Our 2-Fluoro-5-Methoxy-3-(Trifluoromethyl)Benzonitrile, 97% is manufactured under strict quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with the stated specifications. Our quality system supports traceability and is designed to meet the stringent requirements of research and pre-clinical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Purity (GC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.