Description

4-Butoxy-2,6-Difluorobenzonitrile is a specialized fluorinated benzonitrile derivative, serving as a crucial synthetic intermediate in advanced organic chemistry. Its value lies in the strategic placement of fluorine and alkoxy substituents, which are key for modulating the electronic and steric properties of target molecules. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients, as well as by material scientists exploring advanced functional polymers.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and oncology.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides and pesticides, where the difluoro and butoxy groups contribute to biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor in the development of fluorinated liquid crystals and organic light-emitting diode (OLED) materials, where its structure aids in tuning electronic properties.
• Polymer Modification: Acts as a monomer or functionalization agent for creating specialty polymers with enhanced chemical resistance, thermal stability, or specific surface properties.
• Chemical Research & Development: A versatile reagent for academic and industrial R&D in organic synthesis, enabling the introduction of fluorinated aromatic systems.
• Advanced Material Science: Investigated for use in the synthesis of porous organic frameworks (POFs) and other functional materials requiring rigid, fluorinated linkers.

Basic Information

Product Name	4-Butoxy-2,6-Difluorobenzonitrile
CAS No.	1373920-94-5
Molecular Formula	C₁₁H₁₁F₂NO
Molecular Weight	211.21 g/mol
Synonyms	2,6-Difluoro-4-butoxybenzonitrile; 4-Butoxy-2,6-difluorobenzonitrile; Benzonitrile, 4-butoxy-2,6-difluoro-; 1373920-94-5; 4-n-Butoxy-2,6-difluorobenzonitrile; 2,6-Difluoro-4-n-butoxybenzonitrile
EINECS	Contact for details

Quality Control

Our 4-Butoxy-2,6-Difluorobenzonitrile is produced under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing specifications such as assay (by HPLC), related substances, and residual solvents is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat sources and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.