Description

3-Fluoro-5-(Pentafluorosulfur)Benzonitrile is a high-value, multi-functional fluorinated aromatic building block. This compound matters for its unique combination of a nitrile group and a pentafluorosulfanyl (SF5) substituent, which imparts exceptional chemical stability, lipophilicity, and electronic properties to advanced materials. It is primarily needed by R&D chemists and process engineers in the pharmaceutical, agrochemical, and specialty materials industries for synthesizing novel active ingredients and high-performance polymers.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and metabolic diseases.
• Agrochemical Active Ingredient Precursor: Used in the synthesis of novel herbicides, fungicides, and insecticides, where the SF5 group enhances bioactivity and environmental persistence.
• Liquid Crystal & OLED Material Synthesis: Serves as a core building block for fluorine-containing electronic materials, improving charge transport and thermal stability in display technologies.
• Advanced Polymer Monomer: Incorporated into specialty polymers to enhance chemical resistance, lower dielectric constants, and improve material performance in extreme environments.
• Lithium-Ion Battery Electrolyte Additive: Investigated for use in next-generation electrolyte formulations to improve battery safety and cycle life.
• Positron Emission Tomography (PET) Tracer Development: The fluorine-18 isotope can be introduced for creating radiolabeled tracers for medical imaging.

Basic Information

Product Name	3-Fluoro-5-(Pentafluorosulfur)Benzonitrile
CAS No.	1373920-62-7
Molecular Formula	C7HF6NS
Molecular Weight	245.15 g/mol
Synonyms	5-(Pentafluoro-λ6-sulfanyl)-3-fluorobenzonitrile; 3-Fluoro-5-(pentafluorosulfanyl)benzonitrile; Benzonitrile, 3-fluoro-5-(pentafluorosulfanyl)-; 3-Fluoro-5-SF5-benzonitrile; 3-F-SF5-Ph-CN; 3-F-5-SF5-BnCN
EINECS	Contact for details

Quality Control

Our 3-Fluoro-5-(Pentafluorosulfur)Benzonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure high purity and batch-to-batch consistency suitable for sensitive R&D and scale-up processes. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.