Description

2-Ethyl-1-Fluoro-4-Nitrobenzene is a specialized aromatic nitro compound featuring both fluorine and an ethyl substituent, making it a valuable intermediate in advanced organic synthesis. Its unique structure provides a versatile platform for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and agrochemicals. This high-purity building block is essential for research and production chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific functional groups into their target compounds.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those requiring fluorinated aromatic cores for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, where the fluorine atom and nitro group are critical for biological activity.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing fluorinated aromatic compounds used in electronic displays and organic light-emitting diodes.
• Dye & Pigment Intermediate: Employed in the manufacture of specialized dyes and pigments, where the nitro and ethyl groups contribute to color properties and solubility.
• Cross-Coupling Reactions: Acts as a substrate in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) for creating complex biaryl structures.
• Chemical Research & Development: A valuable reagent for academic and industrial R&D focused on fluorination chemistry and nitroarene transformations.

Basic Information

Product Name	2-Ethyl-1-Fluoro-4-Nitrobenzene
CAS No.	1369854-05-6
Molecular Formula	C8H8FNO2
Molecular Weight	169.15 g/mol
Synonyms	1-Ethyl-2-fluoro-4-nitrobenzene; 2-Fluoro-4-nitroethylbenzene; 4-Nitro-2-ethylfluorobenzene; 2-Ethylfluoronitrobenzene; 1-Fluoro-2-ethyl-4-nitrobenzene; 2-Fluoro-1-ethyl-4-nitrobenzene; 4-Nitro-1-ethyl-2-fluorobenzene; 2-Ethyl-4-nitrofluorobenzene
EINECS	Contact for details

Quality Control

Our 2-Ethyl-1-Fluoro-4-Nitrobenzene is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to confirm identity and purity. Certificates of Analysis (COA) documenting all test results are provided with every shipment. We adhere to cGMP principles where applicable to support our customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed when not in use to prevent contamination and moisture absorption.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.