Description

2-Fluoro-4-Isopropylbenzonitrile is a high-purity, versatile fluorinated aromatic nitrile building block. This compound is valued for its unique molecular structure, which combines a fluorine substituent with an isopropyl group on a benzonitrile core, enabling precise modifications in advanced chemical synthesis. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors and CNS-active molecules.
• Agrochemical Synthesis: Serves as a crucial precursor for the manufacture of advanced herbicides, fungicides, and pesticides, leveraging the fluorine atom for enhanced bioactivity and environmental stability.
• Liquid Crystal & OLED Materials: Used in the synthesis of fluorinated components for electronic display materials and organic light-emitting diodes (OLEDs), where its structure contributes to desired electronic and physical properties.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and cyano group transformations to construct complex, functionalized aromatic systems.
• Chemical Research & Development: An essential reagent for academic and industrial R&D labs exploring new reaction methodologies and novel fluorinated compound libraries.

Basic Information

Product Name	2-Fluoro-4-Isopropylbenzonitrile
CAS No.	1369834-93-4
Molecular Formula	C10H10FN
Molecular Weight	163.19 g/mol
Synonyms	4-Isopropyl-2-fluorobenzonitrile; 2-Fluoro-4-(1-methylethyl)benzonitrile; 2-Fluoro-4-propan-2-ylbenzonitrile; Benzonitrile, 2-fluoro-4-(1-methylethyl)-; 1369834-93-4; 2-Fluoro-4-isopropyl-benzonitrile; α,α-Dimethyl-2-fluoro-m-toluonitrile
EINECS	Contact for details

Quality Control

Our 2-Fluoro-4-Isopropylbenzonitrile is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring high-purity intermediates for GMP and non-GMP synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong acids, strong bases, and strong oxidizing agents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.