Description

3-(3-Chloro-4-Fluorophenyl)Benzonitrile is a high-purity, specialized organic intermediate featuring a benzonitrile core substituted with a chlorinated and fluorinated phenyl ring. This compound matters for its role as a critical building block in the synthesis of advanced pharmaceutical agents and agrochemicals, where its unique halogenated aromatic structure enables precise molecular modifications. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors seeking to develop new active ingredients and functional molecules. Our supply ensures consistent quality and reliable availability for your most demanding R&D and scale-up projects.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and other small-molecule drug candidates.
• Agrochemical Synthesis: Serves as a precursor for developing new herbicides, fungicides, and insecticides, leveraging the bioactivity of the halogenated aromatic system.
• Liquid Crystal & OLED Materials: Used in the synthesis of advanced electronic materials for displays and optoelectronics due to its rigid, polarizable molecular structure.
• Organic Ligand Precursor: Functions as a starting material for creating specialized ligands used in catalysis and metal-organic frameworks (MOFs).
• Chemical Research & Development: A versatile building block for academic and industrial research exploring new chemical entities and reaction pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target molecules.

Basic Information

Item	Detail
Product Name	3-(3-Chloro-4-Fluorophenyl)Benzonitrile
CAS No.	1365272-66-7
Molecular Formula	C13H7ClFN
Molecular Weight	231.65 g/mol
Synonyms	3-(3-Chloro-4-fluorophenyl)benzonitrile; [1,1'-Biphenyl]-3-carbonitrile, 3'-chloro-4'-fluoro-; 3'-Chloro-4'-fluoro-[1,1'-biphenyl]-3-carbonitrile; 3-(3-Chloro-4-fluorophenyl)phenyl cyanide; 3-Chloro-4-fluoro-3-cyanobiphenyl; (3-Chloro-4-fluorophenyl)benzonitrile; 3-Cyano-3'-chloro-4'-fluorobiphenyl
EINECS	Contact for details

Quality Control

Our 3-(3-Chloro-4-Fluorophenyl)Benzonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports compliance with cGMP and ISO standards where required for advanced research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The product is light-sensitive and should be stored away from light as indicated.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.