Description

4-(3,5-Dichlorophenyl)-2-Fluorobenzonitrile is a high-value, multi-functional aromatic nitrile building block designed for advanced chemical synthesis. Its molecular architecture, featuring a fluorinated benzonitrile core and a dichlorinated phenyl substituent, makes it a critical intermediate for developing active pharmaceutical ingredients (APIs) and specialty agrochemicals. This compound is essential for research and production chemists in the pharmaceutical, agrochemical, and advanced materials sectors seeking to introduce specific halogenated motifs into complex molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of novel drug candidates, particularly in kinase inhibitor and other small-molecule therapeutic programs.
• Agrochemical Synthesis: Serves as a crucial building block in the manufacture of advanced herbicides, fungicides, and insecticides, leveraging its halogenated structure for bioactivity.
• Ligand and Catalyst Development: Used in organometallic chemistry and catalysis research to create novel ligands for transition metal complexes.
• Material Science Research: Employed in the synthesis of specialty polymers, liquid crystals, and organic electronic materials due to its rigid, aromatic structure.
• Chemical Biology Probes: Utilized as a scaffold for developing molecular probes and fluorescent tags for biological imaging and diagnostic applications.

Basic Information

Product Name	4-(3,5-Dichlorophenyl)-2-Fluorobenzonitrile
CAS No.	1361759-33-2
Molecular Formula	C13H6Cl2FN
Molecular Weight	266.10 g/mol
Synonyms	2-Fluoro-4-(3,5-dichlorophenyl)benzonitrile; 4-(3,5-Dichlorophenyl)-2-fluorobenzonitrile; Benzonitrile, 4-(3,5-dichlorophenyl)-2-fluoro-; 1361759-33-2; 2-Fluoro-4-(3,5-dichlorophenyl)benzonitrile; 4-(3,5-Dichlorophenyl)-2-fluorobenzene carbonitrile
EINECS	Contact for details

Quality Control

Our production of 4-(3,5-Dichlorophenyl)-2-Fluorobenzonitrile adheres to stringent in-process controls and final release testing to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data including HPLC purity, identity confirmation (IR, NMR), and residual solvent analysis. A Certificate of Analysis (COA) detailing all specifications and test results is supplied with every shipment, supporting your quality management systems and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents, strong bases, and strong acids.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.