Description

8-(Trifluoromethyl)-1-Methoxyisoquinoline CAS NO 1357945-53-9 is a specialized heterocyclic building block featuring a trifluoromethyl group, a key structural motif prized in modern chemical synthesis. This compound matters for its role in facilitating the development of novel molecules with enhanced properties such as metabolic stability and lipophilicity. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing complex active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in kinase inhibitor and CNS-targeted therapies.
• Agrochemical Synthesis: Used in the creation of advanced herbicides and fungicides, where the trifluoromethyl group can improve biological activity and environmental stability.
• Material Science Research: Serves as a precursor for organic electronic materials, such as ligands for OLEDs or charge-transport molecules.
• Fluorine Chemistry Building Block: Essential for introducing the trifluoromethyl moiety into complex molecular architectures in medicinal and synthetic chemistry.
• Chemical Biology Probes: Utilized in the design of molecular probes and inhibitors for studying enzyme function and biological pathways.

Basic Information

Item	Details
Product Name	8-(Trifluoromethyl)-1-Methoxyisoquinoline
CAS No.	1357945-53-9
Molecular Formula	C11H8F3NO
Molecular Weight	227.18 g/mol
Synonyms	1-Methoxy-8-(trifluoromethyl)isoquinoline; 8-(Trifluoromethyl)-1-methoxy-isoquinoline; 1-Methoxy-8-trifluoromethylisoquinoline; Isoquinoline, 1-methoxy-8-(trifluoromethyl)-; 1357945-53-9
EINECS	Contact for details

Quality Control

Our 8-(Trifluoromethyl)-1-Methoxyisoquinoline is manufactured under strict quality management protocols. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing purity, impurities, and physical characteristics are provided with each shipment to guarantee traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.