Description

4-Ethyl-1-Fluoro-2-Nitrobenzene is a specialized fluorinated nitroaromatic compound that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both electron-withdrawing nitro and fluorine substituents on the benzene ring, makes it a valuable intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research institutions and chemical manufacturers in the pharmaceutical and agrochemical sectors for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly for fluorinated active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the development of advanced herbicides, pesticides, and fungicides where the fluorine atom enhances biological activity and stability.
• Material Science Research: Serves as a monomer or functionalizing agent in the creation of specialty polymers and liquid crystals.
• Organic Electronics: Investigated as a building block for electron-transport materials and organic semiconductors.
• Dye and Pigment Manufacturing: Intermediate for synthesizing complex, color-fast dyes and functional pigments.
• Cross-Coupling Reactions: A valuable substrate in palladium-catalyzed reactions (e.g., Suzuki, Heck) for creating biaryl structures.

Basic Information

Product Name	4-Ethyl-1-Fluoro-2-Nitrobenzene
CAS No.	1357252-94-8
Molecular Formula	C8H8FNO2
Molecular Weight	169.15 g/mol
Synonyms	1-Ethyl-4-Fluoro-2-Nitrobenzene; 2-Nitro-4-Ethylfluorobenzene; 4-Ethyl-2-Nitrofluorobenzene; 1-Fluoro-4-Ethyl-2-Nitrobenzene; 2-Fluoro-5-Ethylnitrobenzene; 4-Ethyl-2-Nitro-1-Fluorobenzene; (4-Ethyl-2-nitrophenyl) fluoride
EINECS	Contact for details

Quality Control

Our 4-Ethyl-1-Fluoro-2-Nitrobenzene is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality system supports the needs of cGMP (Current Good Manufacturing Practice) for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.