Description

1-Chloro-3-Fluoro-5-(4-Nitrophenyl)Benzene is a high-purity, multi-functional aromatic building block designed for advanced synthetic chemistry. This compound is valued for its unique substitution pattern, which provides distinct electronic and steric properties crucial for constructing complex molecular architectures. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications such as drug discovery, material science, and the synthesis of specialty chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders or as a precursor for kinase inhibitors.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and pesticides, leveraging the nitro and halogen substituents for bioactivity.
• Material Science & OLED Development: Serves as a precursor for electron-transport materials or host materials in organic light-emitting diodes (OLEDs) due to its conjugated system and electron-withdrawing groups.
• Ligand Synthesis: Employed in the preparation of specialized ligands for catalysis, including those used in cross-coupling reactions like Suzuki or Buchwald-Hartwig amination.
• Dye & Pigment Intermediate: Acts as a starting material for synthesizing complex azo dyes and high-performance pigments.
• Academic & Contract Research: Essential for methodological studies in organic synthesis, including novel fluorination and functionalization reactions.

Basic Information

Product Name	1-Chloro-3-Fluoro-5-(4-Nitrophenyl)Benzene
CAS No.	1352318-39-8
Molecular Formula	C12H7ClFNO2
Molecular Weight	251.64 g/mol
Synonyms	3-Chloro-5-Fluoro-4'-Nitro-1,1'-Biphenyl; 4-Nitro-3',5'-Dichloro-4'-Fluorobiphenyl; 1-Chloro-3-fluoro-5-(4-nitrophenyl)benzene; (4-Nitrophenyl)-3-chloro-5-fluorobenzene; 3-Chloro-5-fluoro-4'-nitrobiphenyl; 4'-(3-Chloro-5-fluorophenyl)nitrobenzene; 5-Chloro-3-fluoro-4'-nitro-1,1'-biphenyl
EINECS	Contact for details

Quality Control

Our 1-Chloro-3-Fluoro-5-(4-Nitrophenyl)Benzene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports applications requiring high-purity intermediates for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, the container should be amber-colored or stored in a dark place.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.