Description

2-(3-Fluorophenyl)Benzonitrile is a high-value fluorinated aromatic nitrile building block, essential for advanced organic synthesis. This compound matters for its role in constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and functional materials. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries seeking to introduce specific fluorinated motifs into their target molecules.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, especially kinase inhibitors and central nervous system (CNS) active compounds.
• Agrochemical Synthesis: Used in the preparation of advanced herbicides and pesticides where the fluorophenyl group enhances biological activity and metabolic stability.
• Liquid Crystal & OLED Material Precursor: Serves as a building block for fluorinated liquid crystals and organic light-emitting diode (OLED) materials, contributing to improved electronic properties and thermal stability.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Heck, and other palladium-catalyzed cross-coupling reactions to create biaryl structures.
• Functional Polymer Monomer: Employed in the synthesis of specialty polymers with tailored properties such as chemical resistance and specific refractive indices.
• Chemical Research & Development: A versatile reagent in academic and industrial R&D labs for exploring new synthetic methodologies and creating compound libraries.

Basic Information

Product Name	2-(3-Fluorophenyl)Benzonitrile
CAS No.	1352318-38-7
Molecular Formula	C₁₃H₈FN
Molecular Weight	197.21 g/mol
Synonyms	3'-Fluoro-[1,1'-biphenyl]-2-carbonitrile; 2-(3-Fluorophenyl)benzonitrile; [1,1'-Biphenyl]-2-carbonitrile, 3'-fluoro-; 3-Fluorobiphenyl-2-carbonitrile; 2-Cyano-3'-fluorobiphenyl; (3-Fluorophenyl)(2-cyanophenyl); 2-(3-Fluorophenyl)phenyl cyanide
EINECS	Contact for details

Quality Control

Our 2-(3-Fluorophenyl)Benzonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.