Description

4-(Oxetan-3-Yloxy)-3-(Trifluoromethyl)Benzonitrile is a high-value, multi-functional chemical intermediate characterized by its oxetane ether and trifluoromethyl-substituted benzonitrile structure. This compound matters for its role in facilitating complex molecular synthesis, offering a unique combination of steric and electronic properties that are difficult to achieve with other building blocks. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel small-molecule drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the development of advanced herbicides and fungicides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Material Science Research: Serves as a monomer or precursor for specialty polymers and liquid crystals, leveraging the oxetane ring's polymerization capability.
• Organic Synthesis & Process Chemistry: Employed in academic and industrial R&D for constructing complex heterocycles and fluorinated aromatic systems.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.

Basic Information

Product Name	4-(Oxetan-3-Yloxy)-3-(Trifluoromethyl)Benzonitrile
CAS No.	1349718-17-7
Molecular Formula	C11H8F3NO2
Molecular Weight	243.18 g/mol
Synonyms	3-(Trifluoromethyl)-4-(oxetan-3-yloxy)benzonitrile; 4-(Oxetan-3-yloxy)-3-(trifluoromethyl)benzonitrile; Benzonitrile, 4-(oxetan-3-yloxy)-3-(trifluoromethyl)-; 3-Trifluoromethyl-4-oxetan-3-yloxy-benzonitrile; 1349718-17-7; 4-(Oxetan-3-yloxy)-α,α,α-trifluoro-m-toluonitrile
EINECS	Contact for details

Quality Control

Our 4-(Oxetan-3-Yloxy)-3-(Trifluoromethyl)Benzonitrile is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We support development and commercial projects requiring material that meets GMP or other stringent regulatory guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.