Description

4-Bromo-5-Chloro-2-Fluoro-Benzonitrile is a high-purity, multi-halogenated benzonitrile derivative serving as a critical building block in advanced organic synthesis. Its value lies in providing a versatile, functionalized aromatic core for constructing complex molecules, particularly in the pharmaceutical and agrochemical sectors. This compound is essential for research chemists and process development scientists working on active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging the halogen pattern for bioactivity.
• Material Science Research: Serves as a monomer or functionalization agent in the creation of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Biology: Employed as a probe or labeling reagent due to its reactive nitrile and halogen functional groups.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences industry.

Basic Information

Product Name	4-Bromo-5-Chloro-2-Fluoro-Benzonitrile
CAS No.	1349716-15-9
Molecular Formula	C7H2BrClFN
Molecular Weight	234.45 g/mol
Synonyms	2-Fluoro-4-bromo-5-chlorobenzonitrile; 5-Chloro-4-bromo-2-fluorobenzonitrile; Benzonitrile, 4-bromo-5-chloro-2-fluoro-; 4-Bromo-5-chloro-2-fluorobenzocarbonitrile
EINECS	Contact for details

Quality Control

Our 4-Bromo-5-Chloro-2-Fluoro-Benzonitrile is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring GMP-grade intermediates and materials for regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep the container sealed to prevent moisture absorption and contamination. Store away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.