Description

3,4-Dichloro-2-Fluorobenzonitrile is a high-purity fluorinated aromatic nitrile building block of significant importance in advanced organic synthesis. Its core value lies in its versatile reactivity, where the nitrile group and strategically placed halogen atoms serve as key handles for constructing complex molecular architectures. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those containing fluorinated and chlorinated aromatic systems.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine atom enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the development of organic electronic materials, such as semiconductors and liquid crystals, due to its electron-withdrawing character.
• Custom Synthesis & Contract Manufacturing: A key building block for custom synthesis houses serving the life sciences sector.

Basic Information

Product Name	3,4-Dichloro-2-Fluorobenzonitrile
CAS No.	1349708-60-6
Molecular Formula	C7H2Cl2FN
Molecular Weight	190.00 g/mol
Synonyms	2-Fluoro-3,4-dichlorobenzonitrile; 3,4-Dichloro-2-fluorobenzonitrile; Benzonitrile, 3,4-dichloro-2-fluoro-; 2-Fluoro-3,4-dichlorobenzene carbonitrile; 3,4-Dichloro-2-fluorophenyl cyanide
EINECS	Contact for details

Quality Control

Our 3,4-Dichloro-2-Fluorobenzonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports compliance with cGMP and ISO standards for pharmaceutical and fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥98.0%
Purity (GC)	≥97.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.