Description

3-(3-Chloro-5-Fluorophenyl)Benzonitrile is a high-purity, advanced pharmaceutical intermediate characterized by its distinct benzonitrile core substituted with chloro and fluoro groups. This compound matters for its critical role in the synthesis of complex active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring precise molecular architecture. Pharmaceutical R&D teams and fine chemical manufacturers need it as a key building block for developing new drug candidates, especially in oncology and central nervous system (CNS) research.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the multi-step production of novel Active Pharmaceutical Ingredients (APIs).
• Agrochemical Research: Serves as a building block for developing new herbicides and pesticides with specific activity profiles.
• Material Science: Used in the research and development of specialty polymers and liquid crystals for electronic displays.
• Organic Synthesis: Employed in academic and industrial laboratories for constructing complex aromatic systems in medicinal chemistry.
• Fluorescent Probe Development: Acts as a core structure for synthesizing organic molecules used in bio-imaging and diagnostic assays.

Basic Information

Product Name	3-(3-Chloro-5-Fluorophenyl)Benzonitrile
CAS No.	1345732-63-9
Molecular Formula	C13H7ClFN
Molecular Weight	231.65 g/mol
Synonyms	3-(3-Chloro-5-fluorophenyl)benzonitrile; [1,1'-Biphenyl]-3-carbonitrile, 3'-chloro-5'-fluoro-; 3'-Chloro-5'-fluoro-[1,1'-biphenyl]-3-carbonitrile; 3-(3-Chloro-5-fluorophenyl)phenyl cyanide; 3-Chloro-5-fluorobiphenyl-3-carbonitrile; (3-Chloro-5-fluorophenyl)benzonitrile
EINECS	Contact for details

Quality Control

Our 3-(3-Chloro-5-Fluorophenyl)Benzonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.