Description

n-(3-Fluorobenzyl)Oxetan-3-Amine is a high-value, fluorinated oxetane amine building block of significant interest in modern synthetic chemistry. Its unique structure, combining a reactive oxetane ring with a fluorinated benzyl group, makes it a versatile intermediate for constructing complex molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for applications in medicinal chemistry and crop protection. Its utility lies in enabling the synthesis of novel compounds with potential for enhanced biological activity and improved physicochemical properties.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for introducing the oxetane moiety to modulate solubility, metabolic stability, and potency.
• Medicinal Chemistry Research: Used in high-throughput screening and lead optimization programs to explore structure-activity relationships (SAR) in new drug candidates.
• Agrochemical Synthesis: Serves as a precursor in developing advanced herbicides, fungicides, and insecticides, where the fluorine atom can enhance bioavailability and environmental persistence.
• Ligand and Catalyst Development: Employed in the creation of novel chiral ligands and organocatalysts for asymmetric synthesis.
• Material Science Precursor: Potential use in synthesizing specialty polymers and advanced materials with unique thermal or optical properties.
• Chemical Biology Probes: Useful for labeling and studying biological systems due to the incorporation of both an amine handle and a fluorine tag for potential 19F NMR studies.

Basic Information

Product Name	n-(3-Fluorobenzyl)Oxetan-3-Amine
CAS No.	1341690-67-2
Molecular Formula	C10H12FNO
Molecular Weight	181.21 g/mol
Synonyms	3-[(3-Fluorophenyl)methyl]aminooxetane; Oxetan-3-amine, N-[(3-fluorophenyl)methyl]-; 1-(3-Fluorobenzyl)oxetan-3-amine; N-(3-Fluorobenzyl)-3-aminooxetane; 3-[(3-Fluorobenzyl)amino]oxetane; 3-Aminooxetane, N-(3-fluorobenzyl)-; (Oxetan-3-yl)(3-fluorobenzyl)amine
EINECS	Contact for details

Quality Control

Our n-(3-Fluorobenzyl)Oxetan-3-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for research and process development. Standard testing includes identity confirmation, purity assay, and control of key impurities. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if necessary for long-term storage.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.