Description

2-Bromo-4,6-Difluorobenzonitrile is a high-purity, multi-functional halogenated aromatic nitrile building block. This compound is valued for its unique molecular architecture, which facilitates selective substitution reactions and serves as a critical precursor in advanced synthesis. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for constructing complex molecules, including active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: A key synthon in the development of new drug candidates, particularly for molecules requiring a difluorobenzene core with orthogonal reactivity for further functionalization.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the bromine and fluorine substituents contribute to biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis for asymmetric synthesis.
• Material Science Research: Employed in the synthesis of specialty polymers, liquid crystals, and organic electronic materials due to its aromatic and halogenated structure.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom chemical synthesis services catering to the needs of biotechnology and fine chemical industries.

Basic Information

Product Name	2-Bromo-4,6-Difluorobenzonitrile
CAS No.	1337606-50-4
Molecular Formula	C7H2BrF2N
Molecular Weight	218.00 g/mol
Synonyms	2-Bromo-4,6-difluorobenzonitrile; Benzonitrile, 2-bromo-4,6-difluoro-; 4,6-Difluoro-2-bromobenzonitrile; 2-Bromo-4,6-difluorophenyl cyanide
EINECS	Contact for details

Quality Control

Every batch of 2-Bromo-4,6-Difluorobenzonitrile is manufactured under strict quality management systems. We employ advanced analytical techniques including HPLC, GC, NMR, and MS to ensure identity, purity, and consistency meet the exacting standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.