Description

4-Chloro-6-(Trifluoromethyl)Indoline-2,3-Dione is a high-value, multi-functional heterocyclic building block characterized by its unique indoline-2,3-dione core and halogenated substituents. This compound matters for its critical role as a versatile synthetic intermediate in advanced organic synthesis, enabling the construction of complex molecular architectures. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides and fungicides, leveraging the trifluoromethyl group for enhanced bioactivity and stability.
• Organic Electronic Materials: Serves as a precursor for the development of specialty dyes, pigments, and functional materials for optoelectronic applications.
• Chemical Research & Development: A valuable scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Ligand and Catalyst Development: Potential use in designing novel chelating ligands for catalytic systems in asymmetric synthesis.

Basic Information

Product Name	4-Chloro-6-(Trifluoromethyl)Indoline-2,3-Dione
CAS No.	1332606-83-3
Molecular Formula	C9H3ClF3NO2
Molecular Weight	249.57 g/mol
Synonyms	4-Chloro-6-(trifluoromethyl)indoline-2,3-dione; 4-Chloro-6-(trifluoromethyl)isatin; 4-Chloro-6-(trifluoromethyl)-1H-indole-2,3-dione; 4-Chloro-6-trifluoromethylisatin; 4-Chloro-6-trifluoromethyl-2,3-dioxoindoline; 4-Chloro-6-(trifluoromethyl)-2,3-dihydro-1H-indole-2,3-dione; 1332606-83-3; 4-Cl-6-CF3-isatin
EINECS	Contact for details

Quality Control

Our 4-Chloro-6-(Trifluoromethyl)Indoline-2,3-Dione is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to guarantee supply reliability and batch-to-batch reproducibility for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and reducing agents. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.