Description

4-Fluoro-2-(Trifluoromethoxy)Phenylacetonitrile, 97% is a high-purity fluorinated aromatic nitrile building block of significant interest in advanced organic synthesis. Its unique structure, featuring both fluorine and trifluoromethoxy substituents, makes it a critical intermediate for developing novel compounds with tailored electronic and physicochemical properties. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, particularly in the development of kinase inhibitors, anti-inflammatory agents, and central nervous system (CNS) active compounds.
• Agrochemical Research: Used in the design and synthesis of next-generation herbicides, fungicides, and insecticides, where the fluorine and trifluoromethoxy groups enhance biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorinated liquid crystals and organic light-emitting diode (OLED) materials, where its electronic properties help fine-tune performance.
• Advanced Polymer Chemistry: Employed in the synthesis of specialty polymers and functional materials requiring specific dielectric constants, chemical resistance, or surface properties.
• Chemical Biology & Probe Development: Utilized as a versatile precursor for creating fluorescent probes, radioligands, and other tools for biochemical and diagnostic applications.

Basic Information

Product Name	4-Fluoro-2-(Trifluoromethoxy)Phenylacetonitrile, 97%
CAS No.	1323966-14-8
Molecular Formula	C9H5F4NO
Molecular Weight	219.14 g/mol
Synonyms	2-(4-Fluoro-2-(trifluoromethoxy)phenyl)acetonitrile; (4-Fluoro-2-(trifluoromethoxy)phenyl)acetonitrile; 4-Fluoro-2-(trifluoromethoxy)benzyl cyanide; α-Cyano-4-fluoro-2-(trifluoromethoxy)toluene; 4-Fluoro-2-trifluoromethoxyphenylacetonitrile; F-TFMPA; 1323966-14-8
EINECS	Contact for details

Quality Control

Our 4-Fluoro-2-(Trifluoromethoxy)Phenylacetonitrile, 97% is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and FTIR, to ensure identity, purity, and consistency meet the specified standard of 97% minimum purity. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong acids, strong bases, and strong oxidizing agents. The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.