Description

Linzagolix Choline is a high-purity active pharmaceutical ingredient (API) and key intermediate in advanced therapeutic development. This compound is of significant commercial and research interest due to its role as a selective, orally active gonadotropin-releasing hormone (GnRH) receptor antagonist. It is primarily utilized by pharmaceutical manufacturers and advanced research institutions engaged in the development of treatments for hormone-dependent conditions such as endometriosis and uterine fibroids.

Application

• Primary Active Pharmaceutical Ingredient (API) in finished drug products.
• Key intermediate in the synthesis of advanced GnRH antagonist therapeutics.
• Research and development of treatments for endometriosis.
• Development of therapeutic agents for uterine fibroids (leiomyomas).
• Preclinical and clinical studies in reproductive medicine.
• Reference standard for analytical method development and quality control.
• Process development and scale-up activities in pharmaceutical manufacturing.

Basic Information

Product Name	Linzagolix Choline
CAS No.	1321816-57-2
Molecular Formula	C32H46ClN7O5 • C5H14NO
Molecular Weight	Contact for details
Synonyms	Linzagolix Choline Salt; OBE2109 Choline; N-[(2R)-2-[[(2S)-2-[[(2R)-2-Acetamido-3-(4-chlorophenyl)propanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-3-(1H-imidazol-5-yl)propyl]-N-methyl-L-valinamide Choline Salt; (2-Hydroxyethyl)trimethylammonium; (2R)-N-[(2S)-2-[[(2R)-2-Acetamido-3-(4-chlorophenyl)propanoyl]amino]-3-(1H-indol-3-yl)propanoyl]-N5-methyl-N5-(3-methylbutyl)-L-ornithinamide Choline Salt; TTA-384 Choline; OBE2109 (Choline Salt); Yselty (API component)
EINECS	Contact for details

Quality Control

Our Linzagolix Choline is manufactured under strict quality management systems to ensure it meets the stringent requirements for pharmaceutical intermediates and APIs. Production adheres to current Good Manufacturing Practice (cGMP) principles. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles, ensuring traceability and compliance with your project specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The material is hygroscopic (moisture-sensitive); ensure the container is kept tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Any single unknown impurity	≤0.5%
Residual Solvents (GC)	Complies with ICH Q3C
Water Content (KF)	≤5.0%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.