Description

1-(3-Fluoro-4-Methoxyphenyl)Cyclobutanecarbonitrile is a high-purity fluorinated aromatic nitrile building block of significant interest in advanced organic synthesis. Its unique structure, featuring a cyclobutane ring and a fluorine substituent, makes it a valuable intermediate for constructing complex molecular architectures. This compound is primarily targeted at research and development chemists in the pharmaceutical and agrochemical industries seeking to develop novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, oncology, and inflammation.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and insecticides, where the fluorine atom can enhance biological activity and metabolic stability.
• Liquid Crystal & OLED Material Research: Serves as a precursor for fluorinated aromatic compounds used in electronic display technologies and organic light-emitting diodes (OLEDs).
• Advanced Polymer Chemistry: Employed as a monomer or modifier to introduce rigid, fluorinated segments into specialty polymers, impacting their thermal and chemical resistance.
• Chemical Biology & Probe Development: Useful for synthesizing fluorinated probes and tags for studying biological systems and diagnostic applications.
• Custom Synthesis & Contract Manufacturing: Supplied to CROs and CDMOs for use in client-specific synthesis projects requiring bespoke fluorinated intermediates.

Basic Information

Product Name	1-(3-Fluoro-4-Methoxyphenyl)Cyclobutanecarbonitrile
CAS No.	1314649-16-5
Molecular Formula	C₁₂H₁₂FNO
Molecular Weight	205.23 g/mol
Synonyms	1-(3-Fluoro-4-methoxyphenyl)cyclobutanecarbonitrile; 3-Fluoro-4-methoxy-α-cyclobutanephenylacetonitrile; Cyclobutanecarbonitrile, 1-(3-fluoro-4-methoxyphenyl)-; 1-(3-Fluoro-4-methoxyphenyl)cyclobutane-1-carbonitrile; 1314649-16-5; 1-(3-Fluoro-4-methoxyphenyl)-1-cyanocyclobutane
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch of 1-(3-Fluoro-4-Methoxyphenyl)Cyclobutanecarbonitrile is manufactured under controlled conditions and subjected to comprehensive analytical characterization. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request. We adhere to strict internal quality management protocols to ensure batch-to-batch consistency for your research and development needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.