Description

3-Bromo-5-Fluoro-4-Nitrobenzonitrile is a high-purity, multi-functional aromatic nitrile building block designed for advanced chemical synthesis. This compound is valued for its unique substitution pattern, which provides distinct reactivity and serves as a critical intermediate in the development of complex molecules. It is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging the fluorine and bromine substituents for bioactivity.
• Material Science Research: Serves as a precursor for functionalized polymers, liquid crystals, and organic electronic materials due to its electron-withdrawing nitro and nitrile groups.
• Chemical Biology & Proteomics: Employed as a versatile scaffold for designing molecular probes, enzyme inhibitors, and click chemistry reagents.
• Dye & Pigment Intermediate: Acts as a starting material for synthesizing specialized azo dyes and pigments with specific color and stability properties.
• Cross-Coupling Reactions: The bromine substituent makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to create complex biaryl structures.

Basic Information

Product Name	3-Bromo-5-Fluoro-4-Nitrobenzonitrile
CAS No.	1310918-28-5
Molecular Formula	C7H2BrFN2O2
Molecular Weight	244.99 g/mol
Synonyms	4-Nitro-3-bromo-5-fluorobenzonitrile; Benzonitrile, 3-bromo-5-fluoro-4-nitro-; 3-Bromo-5-fluoro-4-nitrobenzonitrile; 5-Fluoro-3-bromo-4-nitrobenzonitrile; 4-Cyano-2-bromo-6-fluoronitrobenzene; 2-Bromo-6-fluoro-4-cyanointrobenzene; 1310918-28-5
EINECS	Contact for details

Quality Control

Our 3-Bromo-5-Fluoro-4-Nitrobenzonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We support cGMP and ISO standards for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.