Description

Benzonitrile, 5-Formyl-2-(Trifluoromethyl)- is a high-value trifluoromethylated aromatic nitrile building block, distinguished by its formyl and nitrile functional groups. This compound is essential for advanced organic synthesis, enabling the precise construction of complex molecules with tailored electronic and steric properties. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitors and CNS-targeting drugs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances bioactivity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of organic electronic materials, liquid crystals, and polymers requiring specific fluorinated aromatic units.
• Chemical Biology Probes: Useful for synthesizing fluorinated probes and tags for imaging and diagnostic applications.

Basic Information

Product Name	Benzonitrile, 5-Formyl-2-(Trifluoromethyl)-
CAS No.	1289208-38-3
Molecular Formula	C9H4F3NO
Molecular Weight	199.13 g/mol
Synonyms	5-Formyl-2-(trifluoromethyl)benzonitrile; 2-(Trifluoromethyl)-5-formylbenzonitrile; 5-Cyano-2-(trifluoromethyl)benzaldehyde; 2-(Trifluoromethyl)-5-cyanobenzaldehyde; 5-Formyl-2-trifluoromethylbenzonitrile; 2-Trifluoromethyl-5-formylbenzonitrile; 5-Cyano-2-trifluoromethylbenzaldehyde
EINECS	Contact for details

Quality Control

Our Benzonitrile, 5-Formyl-2-(Trifluoromethyl)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to quality supports your R&D and scale-up activities with reliable, high-purity building blocks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.