Description

2-Amino-4-Bromo-6-Fluorobenzonitrile is a high-purity, multi-functional aromatic nitrile building block. This compound matters as a critical intermediate for synthesizing complex molecules, particularly in the pharmaceutical and agrochemical sectors, where its unique halogen and amino substitution pattern enables targeted structural modifications. It is primarily needed by R&D chemists and process development scientists working on active pharmaceutical ingredients (APIs), advanced agrochemicals, and specialty dyes or materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides, leveraging its halogenated benzonitrile core.
• Material Science Research: Serves as a building block for creating functionalized polymers, liquid crystals, and organic electronic materials.
• Dye & Pigment Intermediate: Employed in the production of specialized dyes and colorants due to its amino and cyano functional groups.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Buchwald-Hartwig, and other palladium-catalyzed cross-coupling reactions to create complex biaryl structures.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and tags for biochemical research.

Basic Information

Item	Details
Product Name	2-Amino-4-Bromo-6-Fluorobenzonitrile
CAS No.	1279865-14-3
Molecular Formula	C7H4BrFN2
Molecular Weight	215.02 g/mol
Synonyms	4-Bromo-2-amino-6-fluorobenzonitrile; 2-Amino-4-bromo-6-fluorobenzene carbonitrile; 4-Bromo-6-fluoro-2-aminobenzonitrile; 6-Fluoro-2-amino-4-bromobenzonitrile; Benzonitrile, 2-amino-4-bromo-6-fluoro-; 2-Amino-4-bromo-6-fluorophenyl cyanide; (2-Amino-4-bromo-6-fluorophenyl)carbonitrile
EINECS	Contact for details

Quality Control

Our 2-Amino-4-Bromo-6-Fluorobenzonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed and may require storage under an inert atmosphere for long-term stability. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.