Description

Benzonitrile, 4-Amino-3-Fluoro-2-Methoxy- is a high-purity, multi-functional aromatic nitrile derivative, distinguished by its strategically substituted amino, fluoro, and methoxy groups. This compound serves as a critical advanced pharmaceutical intermediate and a versatile building block for the synthesis of complex organic molecules. It is primarily utilized by R&D chemists and process development teams in the pharmaceutical, agrochemical, and specialty chemical industries to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in oncology and CNS therapeutic areas.
• Agrochemical Synthesis: Used as a building block for developing advanced herbicides, fungicides, and pesticides with enhanced efficacy.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in catalytic processes and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of specialty polymers, liquid crystals, and organic electronic materials.
• Fluorescent Dye and Sensor Chemistry: Acts as a core structure for synthesizing advanced fluorophores and molecular sensors.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds under cGMP conditions.

Basic Information

Product Name	Benzonitrile, 4-Amino-3-Fluoro-2-Methoxy-
CAS No.	1272719-22-8
Molecular Formula	C8H7FN2O
Molecular Weight	166.15 g/mol
Synonyms	4-Amino-3-fluoro-2-methoxybenzonitrile; 2-Methoxy-4-amino-3-fluorobenzonitrile; 3-Fluoro-2-methoxy-4-aminobenzonitrile; 4-Amino-3-fluoro-2-methoxybenzenecarbonitrile; 2-Methoxy-3-fluoro-4-cyanobenzeneamine; 4-Cyano-2-fluoro-5-methoxyaniline; 5-Amino-4-fluoro-6-methoxybenzonitrile; 1272719-22-8 (CAS)
EINECS	Contact for details

Quality Control

Our production of Benzonitrile, 4-Amino-3-Fluoro-2-Methoxy- adheres to stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and MS, to ensure high chemical purity and identity confirmation. We provide detailed Certificates of Analysis (COA) with every shipment, documenting all critical parameters. Our quality commitment supports applications requiring cGMP compliance for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized and should be stored under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.