Description

Cyclopropyl[2-(Trifluoromethoxy)Phenyl]Methanamine is a specialized organic building block featuring a cyclopropylamine core linked to a trifluoromethoxy-substituted phenyl ring. This compound matters for its unique structural motifs, which are highly valuable in modern medicinal chemistry for modulating the pharmacokinetic and physicochemical properties of drug candidates. Pharmaceutical R&D and agrochemical synthesis teams need this high-purity intermediate to develop novel active ingredients with improved metabolic stability and bioavailability.

Application

• Key pharmaceutical intermediate for the synthesis of novel small-molecule therapeutics.
• Building block in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Precursor for agrochemical research, particularly in developing advanced crop protection agents.
• Versatile scaffold in organic synthesis for constructing complex molecules with cyclopropyl and fluorinated aryl groups.
• Used in chemical biology as a probe or ligand to study biological targets and pathways.
• Intermediate for material science research, particularly in developing specialty polymers or advanced organic materials.

Basic Information

Product Name	Cyclopropyl[2-(Trifluoromethoxy)Phenyl]Methanamine
CAS No.	1270354-37-4
Molecular Formula	C11H12F3NO
Molecular Weight	231.21 g/mol
Synonyms	1-[2-(Trifluoromethoxy)phenyl]cyclopropanamine; 1-(2-(Trifluoromethoxy)phenyl)cyclopropan-1-amine; Cyclopropyl(2-(trifluoromethoxy)phenyl)methanamine; (2-(Trifluoromethoxy)phenyl)(cyclopropyl)methanamine; α-Cyclopropyl-2-(trifluoromethoxy)benzenemethanamine; 1270354-37-4; Benzenemethanamine, α-cyclopropyl-2-(trifluoromethoxy)-
EINECS	Contact for details

Quality Control

Our Cyclopropyl[2-(Trifluoromethoxy)Phenyl]Methanamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for advanced pharmaceutical intermediates, ensuring reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is light-sensitive and should be stored away from direct light exposure. Keep the container tightly sealed to minimize exposure to atmospheric moisture. Store separately from strong bases and fluorides.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.